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Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Tlr4, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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toll like receptor  (Proimmune)
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Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Toll Like Receptor, supplied by Proimmune, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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toll  (Upchurch Scientific)
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Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Toll, supplied by Upchurch Scientific, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/toll/pm42087448-643-48-22?v=Upchurch+Scientific
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short chain fatty acid s tf tissue factor tgr5 takeda g protein coupled receptor 5 tir toll interleukin 1 receptor tlr4 toll like  (Takeda)
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Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Short Chain Fatty Acid S Tf Tissue Factor Tgr5 Takeda G Protein Coupled Receptor 5 Tir Toll Interleukin 1 Receptor Tlr4 Toll Like, supplied by Takeda, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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short chain fatty acid s tf tissue factor tgr5 takeda g protein coupled receptor 5 tir toll interleukin 1 receptor tlr4 toll like - by Bioz Stars, 2026-06
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toll  (Cohesion Biosciences)
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Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Toll, supplied by Cohesion Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/toll/pm42076041-258-2-24?v=Cohesion+Biosciences
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nf κb ligand rct randomized controlled trial scfas short chain fatty acids th17 t helper 17 cells tlr4 toll  (Takeda)
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Takeda nf κb ligand rct randomized controlled trial scfas short chain fatty acids th17 t helper 17 cells tlr4 toll
Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
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Arigo Biolaboratories toll
Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Toll, supplied by Arigo Biolaboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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soluble antibody against cd28  (MedChemExpress)
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MedChemExpress soluble antibody against cd28
Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Soluble Antibody Against Cd28, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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lps tlr4 signaling  (MedChemExpress)
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MedChemExpress lps tlr4 signaling
Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Lps Tlr4 Signaling, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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receptor 4 tlr4 signaling  (MedChemExpress)
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MedChemExpress receptor 4 tlr4 signaling
Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
Receptor 4 Tlr4 Signaling, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Histological and molecular expression analysis of IL-29 and TLR4 in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.

Journal: Acta Otorhinolaryngologica Italica

Article Title: Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps

doi: 10.14639/0392-100X-A1222

Figure Lengend Snippet: Histological and molecular expression analysis of IL-29 and TLR4 in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.

Article Snippet: To evaluate the role of TLR4 in IL-29-mediated eosinophil regulation, a TLR4 blockade group (IL-29 50 ng/mL + TAK-242 10 μM, MedChemExpress, HY-11109) and a TAK-242-only intervention group were established.

Techniques: Expressing, Staining, Control, Immunohistochemical staining

Effect of IL-29 on TLR4 and downstream signaling molecule activation. (A) Western blot analysis of TLR4 protein expression; (B) Western blot analysis of p-NF-κB protein expression; (C) Western blot analysis of p-MAPK protein expression. Eosinophils were stimulated with different concentrations of IL-29 (10, 25, 50, 100 ng/mL) for 24 hours. β-actin was used as the internal control. Data were obtained from 3 independent experiments. * indicates p < 0.05.

Journal: Acta Otorhinolaryngologica Italica

Article Title: Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps

doi: 10.14639/0392-100X-A1222

Figure Lengend Snippet: Effect of IL-29 on TLR4 and downstream signaling molecule activation. (A) Western blot analysis of TLR4 protein expression; (B) Western blot analysis of p-NF-κB protein expression; (C) Western blot analysis of p-MAPK protein expression. Eosinophils were stimulated with different concentrations of IL-29 (10, 25, 50, 100 ng/mL) for 24 hours. β-actin was used as the internal control. Data were obtained from 3 independent experiments. * indicates p < 0.05.

Article Snippet: To evaluate the role of TLR4 in IL-29-mediated eosinophil regulation, a TLR4 blockade group (IL-29 50 ng/mL + TAK-242 10 μM, MedChemExpress, HY-11109) and a TAK-242-only intervention group were established.

Techniques: Activation Assay, Western Blot, Expressing, Control

The interventional effect of TAK-242 Blocking TLR4 on IL-29 action. (A) Transwell assay showing changes in eosinophil migration after TLR4 blockade with TAK-242; (B) ELISA of IL-5 secretion after TAK-242 intervention; (C) ELISA of IL-13 secretion after TAK-242 intervention; (D) Western blot analysis of TLR4, p-NF-κB, and p-MAPK protein expression after TAK-242 treatment. Data are presented as mean ± SD. * indicates p < 0.05.

Journal: Acta Otorhinolaryngologica Italica

Article Title: Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps

doi: 10.14639/0392-100X-A1222

Figure Lengend Snippet: The interventional effect of TAK-242 Blocking TLR4 on IL-29 action. (A) Transwell assay showing changes in eosinophil migration after TLR4 blockade with TAK-242; (B) ELISA of IL-5 secretion after TAK-242 intervention; (C) ELISA of IL-13 secretion after TAK-242 intervention; (D) Western blot analysis of TLR4, p-NF-κB, and p-MAPK protein expression after TAK-242 treatment. Data are presented as mean ± SD. * indicates p < 0.05.

Article Snippet: To evaluate the role of TLR4 in IL-29-mediated eosinophil regulation, a TLR4 blockade group (IL-29 50 ng/mL + TAK-242 10 μM, MedChemExpress, HY-11109) and a TAK-242-only intervention group were established.

Techniques: Blocking Assay, Transwell Assay, Migration, Enzyme-linked Immunosorbent Assay, Western Blot, Expressing